Individual and Combined Components of Metabolic Syndrome with Chronic Kidney Disease in Individuals with Hypertension and/or Diabetes Mellitus Accompanied by Primary Health Care
Individual and Combined Components of Metabolic Syndrome with Chronic Kidney Disease in Individuals with Hypertension and/or Diabetes Mellitus Accompanied by Primary Health Care
Blog Article
Luma de O Comini,1 Laura C de Oliveira,1 Luiza D Borges,1 Heloísa H Dias,1 Clara R S Batistelli,1 Luciana S da Silva,2 Tiago R Moreira,3 Rodrigo G da Silva,4 Rosângela M M Cotta1 1Department of Nutrition and Health, Federal University of Viçosa, Viçosa, Minas Gerais, Brazil; 2Medicine School, Federal University of Uberlândia, Uberlândia, Minas sassy spheres candy Gerais, Brazil; 3Department of Nursing and Medicine, Federal University of Viçosa, Viçosa, Minas Gerais, Brazil; 4Clinical Director of the Hemodialysis Service, São João Batista Hospital, Viçosa, Minas Gerais, BrasilCorrespondence: Luma de O CominiDepartment of Nutrition and Health, Federal University of Viçosa, Viçosa, Annex Building of the Biological Sciences Center II, University Campus, s/nº.Sala 101.Federal University of Viçosa, Viçosa, MG CEP: 36570-900, BrazilTel +55 31 3612-7538Fax +55 31 3612-5187Email [email protected]: To identify the associations between MetS and its components and chronic kidney disease (CKD) in a population with arterial hypertension (AH), or diabetes mellitus (DM) accompanied by the Primary Health Care (PHC).
Patients and methods: A cross-sectional study with 788 individuals diagnosed with AH and/or DM followed by PHC of Viçosa, Brazil.Anthropometric, biochemical and clinical measures were performed for the diagnosis of MetS and CKD.MetS was identified using the NCEP-ATPIII criteria.CKD was identified by estimating the glomerular filtration rate using the CKD-EPI equation.
Logistic regression models were used to estimate the chances of CKD associated with MetS and its components and specific combinations of components.Results: The prevalence of MetS reported in the population was 65.4%, that of hidden CKD was 15.4%.
The prevalence of CKD among participants with MetS was 75.2%.The most prevalent component of MetS in the population was AH (96.7%).
Elevated fasting blood glucose, central obesity, and reduced HDL-c were significantly associated with an increased chance of CKD (OR = 2.80, 95% CI 1.76–4.45, OR = 1.
68, 95% CI, 05–2.71, OR = 1.61, CI 95% 1.03–2.
50, respectively).For the multivariate adjustment, the participants with MetS were 2 times more likely to have CKD than those without MetS (OR = 2.07; 95% CI, 1.25–3.
44).The combination of three components of MetS sacred mist sake high blood pressure, abdominal obesity and elevated fasting blood glucose and the combination of four components of MetS high blood pressure, reduced HDL-c, high fasting blood glucose and abdominal obesity were associated with increased odds of CKD (OR = 2.67, CI 95% 1.70–4.
20, OR = 2.50, CI 95% 1.55–4.02, respectively).
Conclusion: MetS, as well as its individual or combined components were independently associated with CKD in the population with AH and/or DM accompanied by PHC.Keywords: high blood pressure, abdominal obesity, hypertriglyceridemia, fasting blood glucose, HDL-c, estimated glomerular filtration rate.